D'Souza is deeply religious and says that, she regularly attends Sunday Mass at St. Anne's Parish (Bandra), and whenever the family is home, a part of their evening is reserved for saying the rosary together. In an interview with The Times of India, she comments, "I keep a Novena every Wednesday at St. Michael’s Church in Mahim." In an interview with Daily News and Analysis, she said that "My communication with God is conversational, I'm God's favourite child; I believe that God has always been kind to me." Her mother tongue is Konkani.